The cannabis plant contains more than a hundred cannabinoids. These compounds directly resemble human endocannabinoids. The major cannabinoid in hemp is CBD and in marijuana THC.
Different THC, CBD does not openly bind to our cannabinoid receptors. However, it stimulates the activity of CB2 and CB1 receptors without taking advantage of them directly. A study by the National Institute of Health (NIH) discovered that CBD causes the body to release more endocannabinoids, especially 2-AG. Additionally, CBD inhibits anandamide degradation.
Scientists are beginning to find several of CBD’s health benefits today:
CBD oil has been promoted by a wide variety of health interests. However, the strongest scientific evidence is its efficiency in treating two rare drug-resistant childhood epilepsy conditions, namely Dravet syndrome (DS) and Lennox-Gastaut syndrome (LGS). Recently the Food and Drug Administration approved the first CBD-derived Epidiolex medication for these conditions. CBD was able to reduce the number of seizures and, in some cases, was able to stop them completely.
CBD oil product may offer an option to treat various types of chronic pain: fibromyalgia, HIV, gout, neuropathic multiple sclerosis, and rheumatoid arthritis. Studies show that applying CBD oil directly to the problem area helps reduce pain and inflammation. CBD works by affecting cannabinoid receptor activity in the body, interacting with neurotransmitters, and reducing inflammation.
They also found that the subjects did not accumulate tolerance to the effects of CBD. Therefore, there was no need to continuously increase the dose. Different pain medications, CBD is not addictive and has no intoxicating effects, providing much relief for people who have chronic pain.
Anxiety and Depression
Clinical trials have revealed that CBD can be effective in reducing various forms of anxiety, including generalized anxiety disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, and post-traumatic stress disorder.
Study participants not only felt better, but they also reported decreased cognitive decline and anxiety. Scientists suggest that, in addition to affecting the endocannabinoid process, CBD may influence the receptors involved in the serotonin modulation, a chemical messenger that plays a role in the regulation of anxiety. Additionally, some studies showed that CBD alleviates depression and assists with psychotic disorders such as schizophrenia.
Cancer Related Symptoms
The researchers also showed that cancer patients treated with THC and CBD, the psychoactive compound in marijuana, experienced a major reduction in pain. Additionally, a one-to-one combination of THC and CBD gave by mouth spray decreased the side effects associated with cancer treatments such as nausea, vomiting, and loss of appetite. Currently, more research is needed on whether CBD may only produce the same beneficial results.
Pregnant and Lactating Women as well as Children
Currently, there is a lack of research on the safety of CBD use for pregnant and lactating women and children. Please consult with your doctor before using CBD product.
Studies show that THC can interrupt the formation of neural networks and cause birth defects related to the nervous system. So, avoid using marijuana during pregnancy. Teens shouldn’t use marijuana either as THC can have an effect on their developing brains.